rs3761847(G;G)

>1.32 x risk of rheumatoid arthritis

Magnitude
2.2Worth knowing
Repute
Bad
Frequency
25%Average of 11 populations
On SNPedia
rs3761847(G;G)
Gene
TRAF1

Frequency

Share of people with G;G in each HapMap population.

  • Luhya (Kenya)55%
  • Maasai (Kenya)44%
  • Yoruba (Nigeria)31%
  • European ancestry (Utah)20%
  • Han Chinese (Beijing)20%
  • Japanese (Tokyo)20%
  • African ancestry (Southwest US)19%
  • Tuscan19%
  • Chinese (Denver)18%
  • Mexican ancestry (Los Angeles)17%
  • Gujarati Indian8%

Other genotypes of rs3761847

  1. A;AGoodnormalTypical · 0.025% of people
  2. A;GBad1.32 x risk of rheumatoid arthritis.Worth knowing · 2.150% of people

All about rs3761847

Notes

From SNPedia

A common genetic variant at the TRAF1-C5 locus on chromosome 9 is associated with an increased risk of anti-CCP-positive rheumatoid arthritis. rs3761847, a SNP located between two genes associated with chronic inflammation (TRAF1 and C5), is associated with increased risk of anti CCP-positive rheumatoid arthritis. The risk allele is (G); the odds ratio reported is 1.32 (95% confidence interval, 1.23 to 1.42; P=4x10-14) PMID 17804836.

References

Source and license

Adapted from rs3761847(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.