rs3775291(C;C)

Common but higher risk of age related macular degeneration

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
64%Average of 11 populations
On SNPedia
rs3775291(G;G)Minus strand
Gene
TLR3

Frequency

Share of people with C;C in each HapMap population.

  • Yoruba (Nigeria)97%
  • Luhya (Kenya)94%
  • Maasai (Kenya)89%
  • African ancestry (Southwest US)86%
  • Gujarati Indian61%
  • Han Chinese (Beijing)55%
  • Japanese (Tokyo)55%
  • Tuscan45%
  • Mexican ancestry (Los Angeles)41%
  • European ancestry (Utah)39%
  • Chinese (Denver)38%

Other genotypes of rs3775291

  1. T;TMost notableGood0.44x decreased risk for dry age related macular degenerationWorth knowing · 2.26% of people
  2. C;TGood0.71x decreased risk for dry age related macular degenerationWorth knowing · 2.130% of people

All about rs3775291

Source and license

Adapted from rs3775291(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.