rs3775291(T;T)

0.44x decreased risk for dry age related macular degeneration

Magnitude
2.2Worth knowing
Repute
Good
Frequency
6%Average of 11 populations
On SNPedia
rs3775291(A;A)Minus strand
Gene
TLR3

Frequency

Share of people with T;T in each HapMap population.

  • Chinese (Denver)14%
  • European ancestry (Utah)13%
  • Mexican ancestry (Los Angeles)12%
  • Japanese (Tokyo)10%
  • Han Chinese (Beijing)7%
  • Tuscan7%
  • Gujarati Indian4%
  • Yoruba (Nigeria)0%
  • African ancestry (Southwest US)0%
  • Luhya (Kenya)0%
  • Maasai (Kenya)0%

Other genotypes of rs3775291

  1. C;TGood0.71x decreased risk for dry age related macular degenerationWorth knowing · 2.130% of people
  2. C;CBadcommon but higher risk of age related macular degenerationWorth knowing · 2.064% of people

All about rs3775291

Notes

From SNPedia

Some association has been reported between polymorphisms in TLR genes and age related macular degeneration(ARMD). However, these variants are not likely to have a major impact of the overall risk of developing macular degeneration.

References

Source and license

Adapted from rs3775291(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.