rs3802177

A SNP in the SLC30A8 gene on chromosome 8. Its most notable genotype is G;G: 1.16x increased risk for type-2 diabetes

Gene
SLC30A8
Location
Chr 8117,172,786 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
28%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableNot rated1.16x increased risk for type-2 diabetesTypical · 0.060% of people
  2. A;GBad1.16x increased risk for type-2 diabetesTypical · 0.032% of people
  3. A;ANot ratednormalTypical · 0.08% of people

SNPedia records rs3802177 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 60% A;G 32% A;A 8%
  • European ancestry (Utah)G;G 57% A;G 39% A;A 4%
  • Han Chinese (Beijing)G;G 29% A;G 47% A;A 24%
  • Japanese (Tokyo)G;G 28% A;G 50% A;A 21%
  • Yoruba (Nigeria)G;G 88% A;G 11% A;A <1%
  • African ancestry (Southwest US)G;G 67% A;G 32% A;A 2%
  • Chinese (Denver)G;G 28% A;G 52% A;A 20%
  • Gujarati IndianG;G 62% A;G 32% A;A 6%
  • Luhya (Kenya)G;G 90% A;G 10% A;A 0%
  • Mexican ancestry (Los Angeles)G;G 62% A;G 33% A;A 5%
  • Maasai (Kenya)G;G 91% A;G 8% A;A <1%
  • TuscanG;G 57% A;G 36% A;A 7%

Conditions, medicines and genes

Other SLC30A8 SNPs

All SLC30A8 SNPs

Notes

From SNPedia

Notes

rs3802177 replicated as significant for type-2 diabetes risk in 1,900 Japanese patients, with odds ratio of 1.16 (CI: 1.05-1.27, p = 4.5 x 10e-3) Note: this SNP is fairly tightly linked (r 2 = 0.83) to another SNP in the SLC30A8 gene also linked to type-2 diabetes, rs13266634

Source and license

Adapted from rs3802177 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.