rs3924999

A SNP in the NRG1 gene on chromosome 8. Its most notable genotype is C;T.

Gene
NRG1
Location
Chr 832,595,840 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
41%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;TMost notableNot ratedNo summary available.Typical · 0.00% of people

SNPedia records rs3924999 on the minus strand: (G;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;T 0%
  • European ancestry (Utah)C;T 0%
  • Han Chinese (Beijing)C;T 0%
  • Japanese (Tokyo)C;T 0%
  • Yoruba (Nigeria)C;T 0%
  • African ancestry (Southwest US)C;T 0%
  • Chinese (Denver)C;T 0%
  • Gujarati IndianC;T 0%
  • Luhya (Kenya)C;T 0%
  • Mexican ancestry (Los Angeles)C;T 0%
  • Maasai (Kenya)C;T 0%
  • TuscanC;T 0%

Conditions, medicines and genes

Other NRG1 SNPs

All NRG1 SNPs

Notes

From SNPedia

Notes

a significant association between rs3924999 and Alzheimer's disease with psychosis

Source and license

Adapted from rs3924999 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.