rs420259(A;A)

Normal risk of Bipolar Disorder.

Magnitude
1.5Minor
Repute
Bad
Frequency
42%Average of 11 populations
On SNPedia
rs420259(T;T)Minus strand
Gene
PALB2

Frequency

Share of people with A;A in each HapMap population.

  • European ancestry (Utah)65%
  • Mexican ancestry (Los Angeles)57%
  • Tuscan54%
  • Gujarati Indian52%
  • Japanese (Tokyo)42%
  • African ancestry (Southwest US)40%
  • Chinese (Denver)38%
  • Han Chinese (Beijing)37%
  • Luhya (Kenya)31%
  • Yoruba (Nigeria)28%
  • Maasai (Kenya)18%

Other genotypes of rs420259

  1. G;GMost notableGoodHalf the risk of developing Bipolar Disorder.Minor · 1.914% of people
  2. A;GGoodPossibly reduced risk of Bipolar Disorder.Minor · 1.544% of people

All about rs420259

Notes

From SNPedia

This is the normal version that most people have. It seems to have a higher risk of bipolar disorder than the rare version, based on preliminary research.

Source and license

Adapted from rs420259(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.