rs4585(G;G)

Slightly higher (1.35x) odds of good metformin response in type 2 diabetics

Magnitude
2.0Worth knowing
Repute
Good
Frequency
28%Average of 11 populations
On SNPedia
rs4585(G;G)
Gene
ATM

Frequency

Share of people with G;G in each HapMap population.

  • Luhya (Kenya)48%
  • Maasai (Kenya)47%
  • Japanese (Tokyo)35%
  • Han Chinese (Beijing)33%
  • African ancestry (Southwest US)32%
  • Chinese (Denver)29%
  • Yoruba (Nigeria)28%
  • European ancestry (Utah)19%
  • Mexican ancestry (Los Angeles)18%
  • Tuscan13%
  • Gujarati Indian10%

Other genotypes of rs4585

  1. G;TNot ratedaverage response to metformin in type 2 diabeticsWorth knowing · 2.045% of people
  2. T;TBadslightly poorer (0.75x) response to metformin in type 2 diabeticsMinor · 1.527% of people

All about rs4585

Source and license

Adapted from rs4585(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.