rs4585(T;T)

Slightly poorer (0.75x) response to metformin in type 2 diabetics

Magnitude
1.5Minor
Repute
Bad
Frequency
27%Average of 11 populations
On SNPedia
rs4585(T;T)
Gene
ATM

Frequency

Share of people with T;T in each HapMap population.

  • Tuscan54%
  • Gujarati Indian52%
  • Mexican ancestry (Los Angeles)39%
  • African ancestry (Southwest US)28%
  • European ancestry (Utah)27%
  • Japanese (Tokyo)22%
  • Han Chinese (Beijing)22%
  • Chinese (Denver)20%
  • Yoruba (Nigeria)13%
  • Maasai (Kenya)12%
  • Luhya (Kenya)10%

Other genotypes of rs4585

  1. G;GMost notableGoodslightly higher (1.35x) odds of good metformin response in type 2 diabeticsWorth knowing · 2.028% of people
  2. G;TNot ratedaverage response to metformin in type 2 diabeticsWorth knowing · 2.045% of people

All about rs4585

Source and license

Adapted from rs4585(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.