rs460184
A SNP in the CFH gene on chromosome 1. Its most notable genotype is T;T: common in clinvar
- Gene
- CFH
- Location
- Chr 1196,747,207 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- Not on consumer chips
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs460184 on the minus strand: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 2 HapMap populations.
- AverageT;T 86%
- European ancestry (Utah)T;T 95%
- Yoruba (Nigeria)T;T 77%
Related
Other CFH SNPs
- rs1061170C;C5.9x risk for AMD; higher mortality among nonagenariansImportant
- rs1061147A;A2.76x increased risk for Age Related Macular Degeneration.Worth knowing
- rs380390G;Gincreased risk for ARMDWorth knowing
- rs1329428C;C2x increased risk for macular degenerationWorth knowing
- rs572515A;ANo summary available.Worth knowing
- rs800292G;G5% higher risk of Age related macular degenerationWorth knowing
- rs460897G;GNo summary available.Typical
- rs529825G;GNo summary available.Typical
Source and license
Adapted from rs460184 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.