rs572515

A SNP in the CFH gene on chromosome 1. Its most notable genotype is A;A.

Gene
CFH
Location
Chr 1196,677,131 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
23%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GNot ratedNo summary available.Typical · 0.066% of people
  2. A;AMost notableNot ratedNo summary available.Worth knowing · 2.07% of people

SNPedia records rs572515 on the minus strand: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 66% A;A 7%
  • European ancestry (Utah)G;G 38% A;A 12%
  • Han Chinese (Beijing)G;G 84% A;A 2%
  • Japanese (Tokyo)G;G 90% A;A 2%
  • Yoruba (Nigeria)G;G 68% A;A 2%
  • African ancestry (Southwest US)G;G 71% A;A 11%
  • Chinese (Denver)G;G 95% A;A 0%
  • Gujarati IndianG;G 46% A;A 12%
  • Luhya (Kenya)G;G 66% A;A 2%
  • Mexican ancestry (Los Angeles)G;G 54% A;A 9%
  • Maasai (Kenya)G;G 62% A;A 5%
  • TuscanG;G 50% A;A 18%

Conditions, medicines and genes

Other CFH SNPs

All CFH SNPs

Notes

From SNPedia

Notes

rs572515 was the most significantly associated of a group of SNPs in the chromosome 1q32-33 region with risk for neovascular age related macular degeneration (p < 10-6).

Source and license

Adapted from rs572515 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.