rs574174

A SNP in the ADAM33 gene on chromosome 20. Its most notable genotype is C;C.

Gene
ADAM33
Location
Chr 203,670,047 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
18%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratedNo summary available.Typical · 0.0

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Other ADAM33 SNPs

All ADAM33 SNPs

Notes

From SNPedia

Notes

rs574174, a SNP in the ADAM33 gene, has been linked to a predisposition to asthma and bronchial hyperresponsiveness. PMID 12110844, PMID 14564349 Exo-proofreading, a versatile SNP scoring technology. Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases. The role of polymorphisms in ADAM33, a disintegrin and metalloprotease 33, in childhood asthma and lung function in two German populations. ADAM33, a new candidate for psoriasis susceptibility. Adam33 polymorphisms are associated with COPD and lung function in long-term tobacco smokers.

C;C

common for Caucasians on the 23andme platform

Source and license

Adapted from rs574174 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.