rs612709
A SNP in the ADAM33 gene on chromosome 20. Its most notable genotype is G;G.
- Gene
- ADAM33
- Location
- Chr 203,671,560 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 22%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Notes
From SNPedia
Show notes, about 130 words
rs612709, a SNP in the ADAM33 gene, has been linked to a predisposition to asthma and bronchial hyperresponsiveness. PMID 12110844, PMID 14564349 Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases. ADAM33, a new candidate for psoriasis susceptibility. Association of ADAM33 gene polymorphisms with adult allergic asthma and rhinitis in a Chinese Han population. Adam33 polymorphisms are associated with COPD and lung function in long-term tobacco smokers. ADAM33 as a psoriasis susceptibility gene in the Han population of northeastern China. ADAM33 genetic polymorphisms, smoking, and rhinoconjunctivitis in Japanese women: the Kyushu Okinawa Maternal and Child Health Study.
G;G
common for Caucasians on the 23andme platform
Source and license
Adapted from rs612709 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.