rs5888(A;A)

Lower HDL cholesterol but higher risk for age-related macular degeneration

Magnitude
2.0Worth knowing
Repute
Not rated
Frequency
9%Average of 11 populations
On SNPedia
rs5888(T;T)Minus strand
Gene
SCARB1

Frequency

Share of people with A;A in each HapMap population.

  • European ancestry (Utah)28%
  • Tuscan23%
  • Gujarati Indian14%
  • Mexican ancestry (Los Angeles)14%
  • Luhya (Kenya)7%
  • Chinese (Denver)6%
  • Han Chinese (Beijing)5%
  • Japanese (Tokyo)4%
  • Maasai (Kenya)3%
  • African ancestry (Southwest US)2%
  • Yoruba (Nigeria)0%

Other genotypes of rs5888

  1. G;GGoodhigher HDL cholesterol but lower risk for age-related macular degenerationMinor · 1.553% of people
  2. A;GMost notableBad3x higher risk for age-related macular degenerationWorth knowing · 2.538% of people

All about rs5888

Source and license

Adapted from rs5888(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.