rs5888(A;G)

3x higher risk for age-related macular degeneration

Magnitude
2.5Worth knowing
Repute
Bad
Frequency
38%Average of 11 populations
On SNPedia
rs5888(C;T)Minus strand
Gene
SCARB1

Frequency

Share of people with A;G in each HapMap population.

  • European ancestry (Utah)54%
  • Gujarati Indian52%
  • Luhya (Kenya)44%
  • Mexican ancestry (Los Angeles)43%
  • Tuscan42%
  • Chinese (Denver)40%
  • Han Chinese (Beijing)37%
  • Japanese (Tokyo)33%
  • African ancestry (Southwest US)27%
  • Maasai (Kenya)26%
  • Yoruba (Nigeria)19%

Other genotypes of rs5888

  1. G;GGoodhigher HDL cholesterol but lower risk for age-related macular degenerationMinor · 1.553% of people
  2. A;ANot ratedlower HDL cholesterol but higher risk for age-related macular degenerationWorth knowing · 2.09% of people

All about rs5888

Source and license

Adapted from rs5888(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.