rs5888(G;G)

Higher HDL cholesterol but lower risk for age-related macular degeneration

Magnitude
1.5Minor
Repute
Good
Frequency
53%Average of 11 populations
On SNPedia
rs5888(C;C)Minus strand
Gene
SCARB1

Frequency

Share of people with G;G in each HapMap population.

  • Yoruba (Nigeria)81%
  • Maasai (Kenya)72%
  • African ancestry (Southwest US)71%
  • Japanese (Tokyo)63%
  • Han Chinese (Beijing)58%
  • Chinese (Denver)55%
  • Luhya (Kenya)50%
  • Mexican ancestry (Los Angeles)43%
  • Tuscan35%
  • Gujarati Indian35%
  • European ancestry (Utah)19%

Other genotypes of rs5888

  1. A;GMost notableBad3x higher risk for age-related macular degenerationWorth knowing · 2.538% of people
  2. A;ANot ratedlower HDL cholesterol but higher risk for age-related macular degenerationWorth knowing · 2.09% of people

All about rs5888

Source and license

Adapted from rs5888(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.