rs6190
A SNP in the NR3C1 gene on chromosome 5. Its most notable genotype is C;C: common in complete genomics
- Gene
- NR3C1
- Location
- Chr 5143,400,772 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 1%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs6190 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 7 HapMap populations.
- AverageC;C 95%
- European ancestry (Utah)C;C 90%
- Han Chinese (Beijing)C;C 96%
- Yoruba (Nigeria)C;C 99%
- Gujarati IndianC;C 95%
- Luhya (Kenya)C;C 99%
- Mexican ancestry (Los Angeles)C;C 91%
- TuscanC;C 96%
Related
Other NR3C1 SNPs
- rs6189C;Ccommon in complete genomicsTypical
- rs6193T;Tcommon in clinvarTypical
- rs6195T;TNo summary available.Typical
- rs6196A;Acommon in complete genomicsTypical
- rs6198T;Tcommon in clinvarTypical
- rs2918419T;Tcommon in complete genomicsTypical
- rs9324921C;Ccommon genotypeTypical
- rs56149945T;Tcommon in clinvarTypical
Notes
From SNPedia
Notes
The association reported in was not replicated in . Glucocorticoid receptor gene haplotype structure and steroid therapy outcome in IBD patients. Molecular mechanism of glucocorticoid resistance in inflammatory bowel disease. Genetic polymorphisms of the glucocorticoid receptor may affect the phenotype of women with anovulatory polycystic ovary syndrome.
Source and license
Adapted from rs6190 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.