rs6198

rs6198 (A3669G) is a SNP located within exon 9 beta of the NR3C1 (Nuclear receptor subfamily 3, group C, member 1 [glucocorticoid receptor]) gene. rs10482605(C) and rs6198 form a haplotype responsible for both regulation of glucocorticoid expression and mRNA stability and therefore theorized to be associated with major depression. journal significant blood pressure associations of a haplotype that is distinguished by rs6198 A/G. Glucocorticoid receptor gene polymorphisms and susceptibility to rheumatoid arthritis. Glucocorticoid receptor gene variant in the 3' untranslated region is associated with multiple measures of blood pressure. Glucocorticoid receptor gene polymorphisms do not affect growth in fetal and early postnatal life. The Generation R Study. No associations between single nucleotide polymorphisms in corticoid receptor genes and heart rate and cortisol responses to a standardized social stress test in adolescents: the TRAILS study. Glucocorticoid receptor-9beta polymorphism is associated with systolic blood pressure and heart growth during early childhood. The Generation R Study. Glucocorticoid receptor gene polymorphism and juvenile idiopathic arthritis. Molecular mechanism of glucocorticoid resistance in inflammatory bowel disease. Glucocorticoid receptor polymorphism is associated with major depression and predominance of depression in the course of bipolar disorder. Genetic polymorphisms of the glucocorticoid receptor may affect the phenotype of women with anovulatory polycystic ovary syndrome. Glucocorticoid receptor polymorphism is associated with lithium response in bipolar patients. Genetic modulation of neural response during working memory in healthy individuals: interaction of glucocorticoid receptor and dopaminergic genes.