rs6196
A SNP in the NR3C1 gene on chromosome 5. Its most notable genotype is A;A: common in complete genomics
- Gene
- NR3C1
- Location
- Chr 5143,281,925 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 14%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 78%
- European ancestry (Utah)A;A 77%
- Han Chinese (Beijing)A;A 90%
- Japanese (Tokyo)A;A 87%
- Yoruba (Nigeria)A;A 68%
- African ancestry (Southwest US)A;A 54%
- Chinese (Denver)A;A 84%
- Gujarati IndianA;A 95%
- Luhya (Kenya)A;A 63%
- Mexican ancestry (Los Angeles)A;A 86%
- Maasai (Kenya)A;A 81%
- TuscanA;A 78%
Related
Other NR3C1 SNPs
- rs6189C;Ccommon in complete genomicsTypical
- rs6190C;Ccommon in complete genomicsTypical
- rs6193T;Tcommon in clinvarTypical
- rs6195T;TNo summary available.Typical
- rs6198T;Tcommon in clinvarTypical
- rs2918419T;Tcommon in complete genomicsTypical
- rs9324921C;Ccommon genotypeTypical
- rs56149945T;Tcommon in clinvarTypical
Notes
From SNPedia
Show notes, about 130 words
Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues. Glucocorticoid receptor gene variant in the 3' untranslated region is associated with multiple measures of blood pressure. Cohort profile: risk patterns and processes for psychopathology emerging during adolescence: the ROOTS project. A comparison of classification methods for predicting Chronic Fatigue Syndrome based on genetic data. Glucocorticoid receptor gene haplotype structure and steroid therapy outcome in IBD patients. Association of FKBP5 gene haplotypes with completed suicide in the Japanese population. Glucocorticoid receptor polymorphism is associated with lithium response in bipolar patients.
Source and license
Adapted from rs6196 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.