rs662(T;T)

~2x higher risk of of coronary heart disease reported in some studies, but lower risk seen in other studies

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
22%Average of 11 populations
On SNPedia
rs662(A;A)Minus strand
Gene
PON1

Frequency

Share of people with T;T in each HapMap population.

  • Tuscan58%
  • Gujarati Indian45%
  • European ancestry (Utah)43%
  • Mexican ancestry (Los Angeles)24%
  • African ancestry (Southwest US)18%
  • Han Chinese (Beijing)16%
  • Maasai (Kenya)12%
  • Chinese (Denver)12%
  • Luhya (Kenya)7%
  • Japanese (Tokyo)7%
  • Yoruba (Nigeria)3%

Other genotypes of rs662

  1. C;TNot rated0.65x lower risk of ovarian cancer; higher risk of coronary heart disease in some studies; somewhat reduced PON catalytic efficiencyTypical · 0.043% of people
  2. C;CNot ratedMixed; conflicting results reported related to stroke and CADMinor · 1.335% of people

All about rs662

Notes

From SNPedia

see discussion at rs662

Source and license

Adapted from rs662(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.