rs6855911

A SNP in the SLC2A9 gene on chromosome 4. Its most notable genotype is A;A: normal, but increased risk of gout

Gene
SLC2A9
Location
Chr 49,934,286 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
26%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBadnormal, but increased risk of goutWorth knowing · 2.055% of people
  2. A;GGood0.62x decreased risk for goutWorth knowing · 2.037% of people
  3. G;GGoodrare, but 0.62x decreased risk for goutWorth knowing · 2.09% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 55% A;G 37% G;G 9%
  • European ancestry (Utah)A;A 45% A;G 49% G;G 6%
  • Han Chinese (Beijing)A;A 98% A;G 2% G;G 0%
  • Japanese (Tokyo)A;A 98% A;G 2% G;G 0%
  • Yoruba (Nigeria)A;A 29% A;G 54% G;G 18%
  • African ancestry (Southwest US)A;A 26% A;G 54% G;G 19%
  • Chinese (Denver)A;A 92% A;G 8% G;G 0%
  • Gujarati IndianA;A 61% A;G 35% G;G 4%
  • Luhya (Kenya)A;A 22% A;G 57% G;G 21%
  • Mexican ancestry (Los Angeles)A;A 46% A;G 40% G;G 14%
  • Maasai (Kenya)A;A 33% A;G 58% G;G 10%
  • TuscanA;A 52% A;G 43% G;G 5%

Conditions, medicines and genes

Other SLC2A9 SNPs

All SLC2A9 SNPs

Notes

From SNPedia

Notes

risk for cardiovascular morbidity and mortality rs6855911 (p = 1.84E-16) although no risk for coronary artery disease or myocardial infarction was observed, rs6855911 was associated with gout. The minor allele had a protective effect, with an allelic odds ratio of 0.62 (CI: 0.52-0.75, p = 3.2x10(-7)).

Source and license

Adapted from rs6855911 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.