rs700518
A SNP in the CYP19A1 gene on chromosome 15. Its most notable genotype is T;T: common in clinvar
- Gene
- CYP19A1
- Location
- Chr 1551,236,915 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 37%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs700518 on the minus strand: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageT;T 47%
- European ancestry (Utah)T;T 19%
- Han Chinese (Beijing)T;T 33%
- Japanese (Tokyo)T;T 39%
- Yoruba (Nigeria)T;T 76%
- African ancestry (Southwest US)T;T 74%
- Chinese (Denver)T;T 31%
- Gujarati IndianT;T 45%
- Luhya (Kenya)T;T 77%
- Mexican ancestry (Los Angeles)T;T 41%
- Maasai (Kenya)T;T 51%
- TuscanT;T 36%
Related
Other CYP19A1 SNPs
- rs78310315C;TUnaffected carrier of an aromatase deficiency mutationImportant
- rs4646A;Acommon in clinvarTypical
- rs10046G;Gcommon in clinvarTypical
- rs700519G;Gcommon in complete genomicsTypical
- rs1062033C;Gincreases susceptibility to postmenopausal osteoporosisTypical
- rs1902584A;Acommon in complete genomicsTypical
- rs1961177C;Ccommon in complete genomicsTypical
- rs2899472C;Ccommon on affy axiom dataTypical
Notes
From SNPedia
Notes
rs700518 is a SNP potentially linked in a gender-specific manner to hypertension
Source and license
Adapted from rs700518 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.