rs78310315
A SNP in the CYP19A1 gene on chromosome 15. Its most notable genotype is C;T: Unaffected carrier of an aromatase deficiency mutation
- Gene
- CYP19A1
- Location
- Chr 1551,211,010 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CGoodcommon in clinvar
- C;TMost notableBadUnaffected carrier of an aromatase deficiency mutation
On SNPedia: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other CYP19A1 SNPs
- rs4646A;Acommon in clinvarTypical
- rs10046G;Gcommon in clinvarTypical
- rs700518T;Tcommon in clinvarTypical
- rs700519G;Gcommon in complete genomicsTypical
- rs1062033C;Gincreases susceptibility to postmenopausal osteoporosisTypical
- rs1902584A;Acommon in complete genomicsTypical
- rs1961177C;Ccommon in complete genomicsTypical
- rs2899472C;Ccommon on affy axiom dataTypical
Notes
From SNPedia
Notes
aka c.1310G>A (p.Cys437Tyr) FTDNA & MyHeritage name: VG15S12228
C;T
Unaffected in absence of a second CYP19A1 gene mutation; see links via main rs-page.
Source and license
Adapted from rs78310315 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.