rs7574865(G;T)

1.3x risk of rheumatoid arthritis; 1.55x risk of SLE; 1.42x risk of Sjögren's syndrome; increased risk of type-1 diabetes; and increased risk of primary biliary cirrhosis.

Magnitude
2.5Worth knowing
Repute
Bad
Frequency
36%Average of 11 populations
On SNPedia
rs7574865(G;T)
Gene
STAT4

Frequency

Share of people with G;T in each HapMap population.

  • Chinese (Denver)55%
  • Gujarati Indian51%
  • Han Chinese (Beijing)47%
  • Mexican ancestry (Los Angeles)46%
  • Japanese (Tokyo)44%
  • European ancestry (Utah)34%
  • Tuscan30%
  • Maasai (Kenya)25%
  • Luhya (Kenya)23%
  • Yoruba (Nigeria)21%
  • African ancestry (Southwest US)21%

Other genotypes of rs7574865

  1. G;GGoodnormal risk of rheumatoid arthritis, SLE, Sjögren's syndrome, type-1 diabetes, and primary biliary cirrhosis.Minor · 1.056% of people
  2. T;TMost notableBad1.69x risk of rheumatoid arthritis; 2.4x risk of SLE; 2.28x risk of Sjögren's syndrome; increased risk of type-1 diabetes; and increased risk of primary biliary cirrhosis.Important · 3.58% of people

All about rs7574865

Source and license

Adapted from rs7574865(G;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.