rs764173488
A SNP in the MUT gene on chromosome 6. Its most notable genotype is T;T: Methylmalonic aciduria (predicted)
- Gene
- MUT
- Location
- Chr 649,447,749 (GRCh38)
- Highest magnitude
- 8.8Very important
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AGoodcommon/normal
- A;TBadCarrier for a methylmalonic aciduria mutation
- T;TMost notableBadMethylmalonic aciduria (predicted)
On SNPedia: (A;A), (A;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other MUT SNPs
- rs121918248A;AMethylmalonic aciduria (predicted)Very important
- rs121918249G;GMethylmalonic aciduria (predicted)Very important
- rs121918251T;TMethylmalonic aciduria (predicted)Very important
- rs121918252A;AMethylmalonic aciduria (predicted)Very important
- rs121918253A;AMethylmalonic aciduria (predicted)Very important
- rs121918254T;TMethylmalonic aciduria (predicted)Very important
- rs121918256A;AMethylmalonic aciduria (predicted)Very important
- rs121918257A;AMethylmalonic aciduria (predicted)Very important
Notes
From SNPedia
Notes
aka c.1481T>A, p.Leu494Ter, L494X; pathogenic variant seen in Japan
A;T
Unaffected in absence of another pathogenic MUT gene mutation. See details via ClinVar link on main SNP/rs# page.
T;T
See discussion and links via main rs-page
Source and license
Adapted from rs764173488 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.