rs8176747
A SNP in the ABO gene on chromosome 9. Its most notable genotype is C;C: common in clinvar
- Gene
- ABO
- Location
- Chr 9133,255,928 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 12%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs8176747 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageC;C 65%
- European ancestry (Utah)C;C 77%
- Han Chinese (Beijing)C;C 67%
- Japanese (Tokyo)C;C 68%
- Yoruba (Nigeria)C;C 48%
Related
Other ABO SNPs
- rs505922C;Cblood type is not O, increased risk for some diseases.Worth knowing
- rs657152A;AA few different minor risk associations; see detailsWorth knowing
- rs1008708453A;AO2 alleles (ABO Type O) may be presentWorth knowing
- rs2519093C;Ccommon/normalTypical
- rs7853989C;CLikely blood group BTypical
- rs8176719-;-likely to be of blood type OTypical
- rs8176740A;ANo summary available.Typical
- rs8176743C;CNo summary available.Typical
Genosets
- Gs129Unable to classify the ABO blood typeWorth knowing
- Gs130AB blood groupWorth knowing
- Gs131B blood groupWorth knowing
- Gs132A blood group; AA or AO at molecular levelWorth knowing
- Gs133B blood groupWorth knowing
- Gs135This genoset identifies an ABO blood group where Type B is likely but Type A possible. Type B from B+O more likely (~8% Caucasian) than Type A.Worth knowing
Genosets combine several genotypes. Twofold checks them in your report.
Notes
From SNPedia
Notes
This SNP is in the ABO gene, and is therefore potentially useful in determing blood group type, such as through the use of genosets. ABO Blood Type
Source and license
Adapted from rs8176747 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.