rs8176749
A SNP in the ABO gene on chromosome 9. Its most notable genotype is C;C.
- Gene
- ABO
- Location
- Chr 9133,255,801 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 12%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs8176749 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageC;C 74%
- European ancestry (Utah)C;C 85%
- Han Chinese (Beijing)C;C 66%
- Japanese (Tokyo)C;C 66%
- Yoruba (Nigeria)C;C 70%
- African ancestry (Southwest US)C;C 81%
- Chinese (Denver)C;C 73%
- Gujarati IndianC;C 57%
- Luhya (Kenya)C;C 71%
- Mexican ancestry (Los Angeles)C;C 85%
- Maasai (Kenya)C;C 77%
- TuscanC;C 84%
Related
Conditions, medicines and genes
Other ABO SNPs
- rs505922C;Cblood type is not O, increased risk for some diseases.Worth knowing
- rs657152A;AA few different minor risk associations; see detailsWorth knowing
- rs1008708453A;AO2 alleles (ABO Type O) may be presentWorth knowing
- rs2519093C;Ccommon/normalTypical
- rs7853989C;CLikely blood group BTypical
- rs8176719-;-likely to be of blood type OTypical
- rs8176740A;ANo summary available.Typical
- rs8176743C;CNo summary available.Typical
Notes
From SNPedia
Notes
This SNP is in the ABO gene, and is therefore potentially useful in determing ABO blood group, such as through the use of genosets.
Source and license
Adapted from rs8176749 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.