rs876659420
A SNP in the MUTYH gene on chromosome 1. Its most notable genotype is A;C: Carrier of a MUTYH-related familial adenomatous polyposis mutation
- Gene
- MUTYH
- Location
- Chr 145,330,515 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- C;CGoodcommon in clinvar
- A;CMost notableBadCarrier of a MUTYH-related familial adenomatous polyposis mutation
SNPedia records rs876659420 on the minus strand: (G;G), (G;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other MUTYH SNPs
- rs34612342C;Cincreased risk for several cancersVery important
- rs36053993T;Tlikely to be at somewhat increased risk for colorectal cancersVery important
- rs77542170C;Cautosomal recessive familial adenomatous polyposis-2 (FAP2)Very important
- rs200165598C;TPossible polyp associated variant, but of uncertain significanceVery important
- rs1060501342-;CCincreased risk for several cancersVery important
- rs121908380G;TCarrier of a MUTYH-related familial adenomatous polyposis mutationImportant
- rs121908381A;CCarrier of a MUTYH-related familial adenomatous polyposis mutationImportant
- rs143353451C;TCarrier of a MUTYH-related familial adenomatous polyposis mutationImportant
Notes
From SNPedia
Notes
A;C
Unaffected in absence of a second MUTYH gene mutation
Source and license
Adapted from rs876659420 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.