rs887829

A SNP in the UGT1A10 gene on chromosome 2. Its most notable genotype is T;T: Higher levels of serum bilirubin, associated with lower risk for coronary artery disease

Gene
UGT1A10
Location
Chr 2233,759,924 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
31%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodHigher levels of serum bilirubin, associated with lower risk for coronary artery diseaseWorth knowing · 2.013% of people
  2. C;CGoodcommonTypical · 0.044% of people

SNPedia records rs887829 on the minus strand: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 13% C;C 44%
  • European ancestry (Utah)T;T 8% C;C 45%
  • Han Chinese (Beijing)T;T 2% C;C 76%
  • Japanese (Tokyo)T;T 5% C;C 71%
  • Yoruba (Nigeria)T;T 27% C;C 27%
  • African ancestry (Southwest US)T;T 14% C;C 23%
  • Chinese (Denver)T;T 2% C;C 73%
  • Gujarati IndianT;T 22% C;C 33%
  • Luhya (Kenya)T;T 21% C;C 19%
  • Mexican ancestry (Los Angeles)T;T 7% C;C 45%
  • Maasai (Kenya)T;T 23% C;C 26%
  • TuscanT;T 9% C;C 51%

Conditions, medicines and genes

Other UGT1A10 SNPs

All UGT1A10 SNPs

Notes

From SNPedia

Notes

rs887829 is a SNP in the UGT1A1 gene. The minor allele of this SNP has been reported to be associated with higher levels of serum bilirubin, which has an inverse correlation with coronary artery disease. . This study of 2,000+ patients reports a recessive protective effect against coronary artery disease for the minor allele, with an age-adjusted odds ratio of 0.24 (CI: 0.10-0.60, p=0.0014).

Source and license

Adapted from rs887829 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.