rs966221(A;G)

1.5x increased stroke risk

Magnitude
0.0Typical
Repute
Bad
Frequency
43%Average of 11 populations
On SNPedia
rs966221(C;T)Minus strand
Gene
PDE4D

Frequency

Share of people with A;G in each HapMap population.

  • European ancestry (Utah)57%
  • Tuscan53%
  • African ancestry (Southwest US)52%
  • Yoruba (Nigeria)51%
  • Maasai (Kenya)44%
  • Luhya (Kenya)44%
  • Mexican ancestry (Los Angeles)42%
  • Gujarati Indian42%
  • Han Chinese (Beijing)34%
  • Chinese (Denver)29%
  • Japanese (Tokyo)21%

Other genotypes of rs966221

  1. G;GMost notableBad1.5x increased stroke risk certain populationsMinor · 1.524% of people
  2. A;AGoodnormalTypical · 0.033% of people

All about rs966221

Source and license

Adapted from rs966221(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.