rs966221(G;G)

1.5x increased stroke risk certain populations

Magnitude
1.5Minor
Repute
Bad
Frequency
24%Average of 11 populations
On SNPedia
rs966221(C;C)Minus strand
Gene
PDE4D

Frequency

Share of people with G;G in each HapMap population.

  • Mexican ancestry (Los Angeles)44%
  • Tuscan36%
  • African ancestry (Southwest US)30%
  • Yoruba (Nigeria)30%
  • Luhya (Kenya)30%
  • European ancestry (Utah)29%
  • Maasai (Kenya)27%
  • Gujarati Indian27%
  • Chinese (Denver)6%
  • Han Chinese (Beijing)4%
  • Japanese (Tokyo)2%

Other genotypes of rs966221

  1. A;GBad1.5x increased stroke riskTypical · 0.043% of people
  2. A;AGoodnormalTypical · 0.033% of people

All about rs966221

Source and license

Adapted from rs966221(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.