rs104894005
A SNP in the GCK gene on chromosome 7. Its most notable genotype is A;C: associated with MODY2; maturity onset of diabetes in the young (type 2)
- Gene
- GCK
- Location
- Chr 744,147,678 (GRCh38)
- Highest magnitude
- 2.0Worth knowing
- Tested on
- AncestryDNA
- Minor allele frequency
- <1%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- C;CGoodcommon in clinvar
- A;CMost notableBadassociated with MODY2; maturity onset of diabetes in the young (type 2)
SNPedia records rs104894005 on the minus strand: (G;G), (G;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other GCK SNPs
- rs104894006A;GDiabetes, late-onset noninsulin-dependent (predicted)Very important
- rs1799884T;T2.7x increased risk for Type 2 Diabetes. Mothers have babies 54g heavier.Important
- rs80356654A;Tassociated with MODY2; maturity onset of diabetes in the young (type 2)Worth knowing
- rs80356655A;Gassociated with MODY2; maturity onset of diabetes in the young (type 2)Worth knowing
- rs104894008C;Tassociated with MODY2; maturity onset of diabetes in the young (type 2)Worth knowing
- rs104894009C;Gassociated with MODY2; maturity onset of diabetes in the young (type 2)Worth knowing
- rs104894011A;Cassociated with MODY2; maturity onset of diabetes in the young (type 2)Worth knowing
- rs104894016C;Tassociated with MODY2; maturity onset of diabetes in the young (type 2)Worth knowing
Source and license
Adapted from rs104894005 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.