rs13306435
A SNP in the IL6 gene on chromosome 7. Its most notable genotype is T;T: common in complete genomics
- Gene
- IL6
- Location
- Chr 722,731,420 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 3%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageT;T 98%
- European ancestry (Utah)T;T 100%
- Han Chinese (Beijing)T;T 98%
- Japanese (Tokyo)T;T 93%
- Yoruba (Nigeria)T;T 100%
Related
Conditions, medicines and genes
Other IL6 SNPs
- rs1800795C;Cless IL6; certain risks, see detailsWorth knowing
- rs1524107C;Ccommon in complete genomicsTypical
- rs2066992G;Gcommon in complete genomicsTypical
- rs2069827G;GNo summary available.Typical
- rs2069830C;Ccommon in complete genomicsTypical
- rs2069849C;Ccommon genotypeTypical
- rs2069861C;CNo summary available.Typical
Notes
From SNPedia
Notes
A haplotype of the IL6 gene appears to be overrepresented in sciatica patients.PMID 15733644, PMID 18321738. The haplotype consists of SNPs rs1800797-rs1800796- rs1800795-rs13306435.
Source and license
Adapted from rs13306435 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.