rs2066992
A SNP in the IL6 gene on chromosome 7. Its most notable genotype is G;G: common in complete genomics
- Gene
- IL6
- Location
- Chr 722,728,630 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 28%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 52%
- European ancestry (Utah)G;G 90%
- Han Chinese (Beijing)G;G 7%
- Japanese (Tokyo)G;G 4%
- Yoruba (Nigeria)G;G 91%
- African ancestry (Southwest US)G;G 84%
- Chinese (Denver)G;G 5%
- Gujarati IndianG;G 38%
- Luhya (Kenya)G;G 64%
- Mexican ancestry (Los Angeles)G;G 47%
- Maasai (Kenya)G;G 57%
- TuscanG;G 89%
Related
Conditions, medicines and genes
Other IL6 SNPs
- rs1800795C;Cless IL6; certain risks, see detailsWorth knowing
- rs1524107C;Ccommon in complete genomicsTypical
- rs2069827G;GNo summary available.Typical
- rs2069830C;Ccommon in complete genomicsTypical
- rs2069849C;Ccommon genotypeTypical
- rs2069861C;CNo summary available.Typical
- rs13306435T;Tcommon in complete genomicsTypical
Notes
From SNPedia
Notes
rs2066992 coronary artery disease 190 affected Asian Indian sibling pairs
Source and license
Adapted from rs2066992 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.