rs1524107
A SNP in the IL6 gene on chromosome 7. Its most notable genotype is C;C: common in complete genomics
- Gene
- IL6
- Location
- Chr 722,728,600 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 28%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageC;C 53%
- European ancestry (Utah)C;C 90%
- Han Chinese (Beijing)C;C 7%
- Japanese (Tokyo)C;C 4%
- Yoruba (Nigeria)C;C 92%
- African ancestry (Southwest US)C;C 84%
- Chinese (Denver)C;C 5%
- Gujarati IndianC;C 38%
- Luhya (Kenya)C;C 65%
- Mexican ancestry (Los Angeles)C;C 47%
- Maasai (Kenya)C;C 57%
- TuscanC;C 89%
Related
Other IL6 SNPs
- rs1800795C;Cless IL6; certain risks, see detailsWorth knowing
- rs2066992G;Gcommon in complete genomicsTypical
- rs2069827G;GNo summary available.Typical
- rs2069830C;Ccommon in complete genomicsTypical
- rs2069849C;Ccommon genotypeTypical
- rs2069861C;CNo summary available.Typical
- rs13306435T;Tcommon in complete genomicsTypical
Notes
From SNPedia
Notes
An IL-6 haplotype on human chromosome 7p21 confers risk for impaired renal function in type 2 diabetic patients. C-reactive protein, interleukin-6, and prostate cancer risk in men aged 65 years and older. Association of genetic variation in serum amyloid-A with cardiovascular disease and interactions with IL6, IL1RN, IL1beta and TNF genes in the Cardiovascular Health Study.
Source and license
Adapted from rs1524107 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.