rs2069830

A SNP in the IL6 gene on chromosome 7. Its most notable genotype is C;C: common in complete genomics

Gene
IL6
Location
Chr 722,727,518 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
2%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodcommon in complete genomicsTypical · 0.092% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 8 HapMap populations.

  • AverageC;C 92%
  • European ancestry (Utah)C;C 100%
  • Han Chinese (Beijing)C;C 99%
  • Japanese (Tokyo)C;C 99%
  • Yoruba (Nigeria)C;C 83%
  • African ancestry (Southwest US)C;C 79%
  • Luhya (Kenya)C;C 86%
  • Mexican ancestry (Los Angeles)C;C 98%
  • Maasai (Kenya)C;C 92%

Conditions, medicines and genes

Other IL6 SNPs

All IL6 SNPs

Notes

From SNPedia

Notes

stroke rs2069830(T) (frequency = 5%) protective among non-smokers (OR = 0.30, 95% CI=0.11-.082, p=0.02), but not among smokers (OR = 1.63, 95% CI=0.48-5.58, p=0.43)

Source and license

Adapted from rs2069830 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.