rs17076812

A SNP in the MCPH1 gene on chromosome 8. Its most notable genotype is A;A: common in complete genomics

Gene
MCPH1
Location
Chr 86,421,917 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe
Minor allele frequency
12%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodcommon in complete genomicsTypical · 0.078% of people

On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 78%
  • European ancestry (Utah)A;A 66%
  • Han Chinese (Beijing)A;A 93%
  • Japanese (Tokyo)A;A 90%
  • Yoruba (Nigeria)A;A 66%
  • African ancestry (Southwest US)A;A 74%
  • Chinese (Denver)A;A 96%
  • Gujarati IndianA;A 79%
  • Luhya (Kenya)A;A 65%
  • Mexican ancestry (Los Angeles)A;A 91%
  • Maasai (Kenya)A;A 62%
  • TuscanA;A 74%

Other MCPH1 SNPs

All MCPH1 SNPs

Notes

From SNPedia

Notes

mentioned as potentially affecting grey matter volume, sample size tiny

Source and license

Adapted from rs17076812 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.