rs2916733

A SNP in the MCPH1 gene on chromosome 8. Its most notable genotype is G;G: common in complete genomics

Gene
MCPH1
Location
Chr 86,465,757 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
34%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in complete genomicsTypical · 0.038% of people

SNPedia records rs2916733 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 38%
  • European ancestry (Utah)G;G 66%
  • Han Chinese (Beijing)G;G 27%
  • Japanese (Tokyo)G;G 21%
  • Yoruba (Nigeria)G;G 22%
  • African ancestry (Southwest US)G;G 25%
  • Chinese (Denver)G;G 26%
  • Gujarati IndianG;G 46%
  • Luhya (Kenya)G;G 19%
  • Mexican ancestry (Los Angeles)G;G 76%
  • Maasai (Kenya)G;G 25%
  • TuscanG;G 66%

Other MCPH1 SNPs

All MCPH1 SNPs

Source and license

Adapted from rs2916733 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.