rs2442513

A SNP in the MCPH1 gene on chromosome 8. Its most notable genotype is T;T: common genotype

Gene
MCPH1
Location
Chr 86,439,029 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
7%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon genotypeTypical · 0.080% of people
  2. G;GGoodcommon in clinvarTypical · 0.03% of people
  3. A;ANot ratedNo summary available.Typical · 0.00% of people

SNPedia records rs2442513 on the minus strand: (A;A), (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 80% G;G 3% A;A 0%
  • European ancestry (Utah)T;T 99% G;G 0% A;A 0%
  • Han Chinese (Beijing)T;T 99% G;G 0% A;A 0%
  • Japanese (Tokyo)T;T 99% G;G 0% A;A 0%
  • Yoruba (Nigeria)T;T 56% G;G 6% A;A 0%
  • African ancestry (Southwest US)T;T 58% G;G 5% A;A 0%
  • Chinese (Denver)T;T 99% G;G 0% A;A 0%
  • Gujarati IndianT;T 92% G;G 0% A;A 0%
  • Luhya (Kenya)T;T 45% G;G 10% A;A 0%
  • Mexican ancestry (Los Angeles)T;T 93% G;G 0% A;A 0%
  • Maasai (Kenya)T;T 47% G;G 13% A;A 0%
  • TuscanT;T 97% G;G 0% A;A 0%

Other MCPH1 SNPs

All MCPH1 SNPs

Source and license

Adapted from rs2442513 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.