rs1800932
A SNP in the MSH6 gene on chromosome 2. Its most notable genotype is A;A: common in clinvar
- Gene
- MSH6
- Location
- Chr 247,790,942 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 10%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 10 HapMap populations.
- AverageA;A 82%
- European ancestry (Utah)A;A 63%
- Han Chinese (Beijing)A;A 100%
- Japanese (Tokyo)A;A 98%
- Yoruba (Nigeria)A;A 78%
- African ancestry (Southwest US)A;A 83%
- Gujarati IndianA;A 88%
- Luhya (Kenya)A;A 86%
- Mexican ancestry (Los Angeles)A;A 81%
- Maasai (Kenya)A;A 84%
- TuscanA;A 58%
Related
Other MSH6 SNPs
- rs587776706T;TMismatch repair cancer syndrome (predicted)Very important
- rs1800937A;CLynch syndrome, pathogenic mutationVery important
- rs63749821-;TALikely miscall in Ancestry data; otherwise, Lynch syndrome, pathogenic mutationVery important
- rs63749843C;TLynch syndrome, pathogenic mutationVery important
- rs63749873C;GLynch syndrome, pathogenic mutationVery important
- rs63749874-;AAGALynch syndrome, pathogenic mutationVery important
- rs63749919A;GLynch syndromeVery important
- rs63749938-;ALynch Syndrome, pathogenic mutationVery important
Source and license
Adapted from rs1800932 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.