rs1801268
A SNP in the DPYD gene on chromosome 1. Its most notable genotype is C;C: common genotype
- Gene
- DPYD
- Location
- Chr 197,079,071 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs1801268 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 3 HapMap populations.
- AverageC;C 99%
- African ancestry (Southwest US)C;C 98%
- Gujarati IndianC;C 99%
- TuscanC;C 99%
Related
Other DPYD SNPs
- rs1801160T;T5-fluorouracil toxicity (?)Important
- rs3918290T;T5-fluorouracil toxicity, dihydropyrimidine dehydrogenase deficiencyImportant
- rs55886062C;C5-fluorouracil toxicityImportant
- rs67376798A;A5-fluorouracil toxicityImportant
- rs1801159T;Tcommon in clinvarTypical
- rs1801265G;Gcommon in clinvarTypical
- rs2297595T;Tcommon on affy axiom dataTypical
Source and license
Adapted from rs1801268 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.