rs2297595
A SNP in the DPYD gene on chromosome 1. Its most notable genotype is T;T: common on affy axiom data
- Gene
- DPYD
- Location
- Chr 197,699,535 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 7%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageT;T 90%
- European ancestry (Utah)T;T 86%
- Han Chinese (Beijing)T;T 97%
- Japanese (Tokyo)T;T 97%
- Yoruba (Nigeria)T;T 97%
- African ancestry (Southwest US)T;T 89%
- Chinese (Denver)T;T 98%
- Gujarati IndianT;T 93%
- Luhya (Kenya)T;T 78%
- Mexican ancestry (Los Angeles)T;T 84%
- Maasai (Kenya)T;T 86%
- TuscanT;T 80%
Related
Other DPYD SNPs
- rs1801160T;T5-fluorouracil toxicity (?)Important
- rs3918290T;T5-fluorouracil toxicity, dihydropyrimidine dehydrogenase deficiencyImportant
- rs55886062C;C5-fluorouracil toxicityImportant
- rs67376798A;A5-fluorouracil toxicityImportant
- rs1801159T;Tcommon in clinvarTypical
- rs1801265G;Gcommon in clinvarTypical
- rs1801268C;Ccommon genotypeTypical
Source and license
Adapted from rs2297595 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.