rs2070672

A SNP in the CYP2E1 gene on chromosome 10. Its most notable genotype is G;G: CYP2E1*7_-352A>G homozygote

Gene
CYP2E1
Location
Chr 10133,527,044 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
12%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AGoodnormalTypical · 0.074% of people
  2. A;GNot ratedcarrier of one CYP2E1*7_-352A>G alleleTypical · 0.024% of people
  3. G;GMost notableBadCYP2E1*7_-352A>G homozygoteWorth knowing · 2.02% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 74% A;G 24% G;G 2%
  • European ancestry (Utah)A;A 93% A;G 7% G;G 0%
  • Han Chinese (Beijing)A;A 62% A;G 33% G;G 5%
  • Japanese (Tokyo)A;A 54% A;G 43% G;G 4%
  • Yoruba (Nigeria)A;A 74% A;G 24% G;G 3%
  • African ancestry (Southwest US)A;A 79% A;G 21% G;G 0%
  • Chinese (Denver)A;A 69% A;G 31% G;G 0%
  • Gujarati IndianA;A 52% A;G 41% G;G 8%
  • Luhya (Kenya)A;A 81% A;G 16% G;G 3%
  • Mexican ancestry (Los Angeles)A;A 83% A;G 17% G;G 0%
  • Maasai (Kenya)A;A 75% A;G 24% G;G 1%
  • TuscanA;A 93% A;G 7% G;G 0%

Other CYP2E1 SNPs

All CYP2E1 SNPs

Notes

From SNPedia

Notes

rs2070672 is a SNP in the CYP2E1 gene. The rs2070672(G) allele defines the CYP2E1*7_-352A>G variant.

Source and license

Adapted from rs2070672 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.