rs915909

A SNP in the CYP2E1 gene on chromosome 10. Its most notable genotype is C;C: normal

Gene
CYP2E1
Location
Chr 10133,533,893 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, FamilyTreeDNA
Minor allele frequency
3%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGoodnormalTypical · 0.094% of people
  2. C;TNot ratedcarrier of one CYP2E1_6498C>T(I321I) alleleTypical · 0.05% of people
  3. G;GNot ratedNo summary available.Typical · 0.00% of people
  4. T;TGoodCYP2E1_6498C>T(I321I) homozygoteTypical · 0.01% of people

On SNPedia: (C;C), (C;T), (G;G), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageC;C 94% C;T 5% G;G 0% T;T 1%
  • European ancestry (Utah)C;C 100% C;T 0% G;G 0% T;T 0%
  • Han Chinese (Beijing)C;C 100% C;T 0% G;G 0% T;T 0%
  • Japanese (Tokyo)C;C 100% C;T 0% G;G 0% T;T 0%
  • Yoruba (Nigeria)C;C 77% C;T 18% G;G 0% T;T 5%

Other CYP2E1 SNPs

All CYP2E1 SNPs

Notes

From SNPedia

Notes

rs915909 is a SNP in the CYP2E1 gene. The rs915909(T) allele defines the CYP2E1_6498C>T(I321I) variant.

Source and license

Adapted from rs915909 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.