rs3813867
A SNP in the CYP2E1 gene on chromosome 10. Its most notable genotype is C;C: CYP2E1_-1295G>C homozygote
- Gene
- CYP2E1
- Location
- Chr 10133,526,101 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 10%
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CMost notableNot ratedCYP2E1_-1295G>C homozygote
- C;GNot ratedcarrier of one CYP2E1_-1295G>C allele
- G;GGoodnormal
On SNPedia: (C;C), (C;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageC;C 4% C;G 23% G;G 73%
- European ancestry (Utah)C;C 0% C;G 12% G;G 88%
- Han Chinese (Beijing)C;C 11% C;G 36% G;G 53%
- Japanese (Tokyo)C;C 5% C;G 32% G;G 64%
- Yoruba (Nigeria)C;C 0% C;G 13% G;G 87%
Related
Other CYP2E1 SNPs
- rs2070672G;GCYP2E1*7_-352A>G homozygoteWorth knowing
- rs2070676G;GCYP2E1*1B homozygoteWorth knowing
- rs2515641T;TCYP2E1_10463T>C(F421F) homozygoteWorth knowing
- rs915908G;Gcommon in complete genomicsTypical
- rs915909C;CnormalTypical
- rs2031920C;CnormalTypical
- rs2070673A;ACYP2E1*7_-333T>A homozygoteTypical
- rs3813865G;Gcommon in complete genomicsTypical
Notes
From SNPedia
Notes
Also known as CYP2E1_-1295G>C, this SNP is reported to mark the c2 allele of CYP2E1. The rs3813867(C) allele defines the CYP2E1_-1295G>C variant allele.
Source and license
Adapted from rs3813867 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.