rs28624811
A SNP in the LOC102723722 gene on chromosome 22. Its most notable genotype is G;G.
- Gene
- LOC102723722
- Location
- Chr 2242,131,531 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, FamilyTreeDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 9 HapMap populations.
- AverageG;G 43%
- Han Chinese (Beijing)G;G 64%
- Japanese (Tokyo)G;G 76%
- African ancestry (Southwest US)G;G 28%
- Chinese (Denver)G;G 74%
- Gujarati IndianG;G 33%
- Luhya (Kenya)G;G 10%
- Mexican ancestry (Los Angeles)G;G 55%
- Maasai (Kenya)G;G 8%
- TuscanG;G 40%
Related
Conditions, medicines and genes
Other LOC102723722 SNPs
- rs1135824C;CTwo copies of CYP2D6*3B non-functioning variantVery important
- rs5030867G;GCYP2D6*7 homozygoteVery important
- rs1065852A;AHomozygous for CYP2D6 decreased or non-functioning variants; possibly less response to some drugs, including tamoxifenImportant
- rs3892097T;TCYP2D6 poor metabolizer; many associations related to drug metabolismImportant
- rs5030655-;-CYP2D6*6 poor metabolizer phenotypeImportant
- rs28371733G;GHomozygous for non-functioning CYP2D6*4H variant.Important
- rs72549354C;CTwo CYP2D6*20 alleles; significantly lowered metabolism of certain drugsImportant
- rs1135840G;GHomozygous for CYP2D6 variants (non-CYP2D6*1)Worth knowing
Notes
From SNPedia
Notes
a variation in CYP2D6
Source and license
Adapted from rs28624811 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.