rs5030867
A SNP in the LOC102723722 gene on chromosome 22. Its most notable genotype is G;G: CYP2D6*7 homozygote
- Gene
- LOC102723722
- Location
- Chr 2242,127,856 (GRCh38)
- Highest magnitude
- 4.0Very important
- Tested on
- 23andMe, AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- T;TGoodnormal
- G;TNot ratedcarrier of one CYP2D6*7 allele
- G;GMost notableNot ratedCYP2D6*7 homozygote
SNPedia records rs5030867 on the minus strand: (A;A), (A;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other LOC102723722 SNPs
- rs1135824C;CTwo copies of CYP2D6*3B non-functioning variantVery important
- rs1065852A;AHomozygous for CYP2D6 decreased or non-functioning variants; possibly less response to some drugs, including tamoxifenImportant
- rs3892097T;TCYP2D6 poor metabolizer; many associations related to drug metabolismImportant
- rs5030655-;-CYP2D6*6 poor metabolizer phenotypeImportant
- rs28371733G;GHomozygous for non-functioning CYP2D6*4H variant.Important
- rs72549354C;CTwo CYP2D6*20 alleles; significantly lowered metabolism of certain drugsImportant
- rs1135840G;GHomozygous for CYP2D6 variants (non-CYP2D6*1)Worth knowing
- rs5030656-;-CYP2D6*9 homozygoteWorth knowing
Genosets
Genosets combine several genotypes. Twofold checks them in your report.
Notes
From SNPedia
Notes
rs5030867, also known as 2935A>C or H324P, is a SNP in the CYP2D6 gene. The rs5030867(C) allele defines the CYP2D6*7 variant, which is inactive.
Source and license
Adapted from rs5030867 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.