rs28940577
A SNP in the MEFV gene on chromosome 16. Its most notable genotype is C;T: carrier of a Familial Mediterranean Fever allele
- Gene
- MEFV
- Location
- Chr 163,243,410 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- 23andMe
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- T;TGoodcommon in complete genomics
- C;TMost notableBadcarrier of a Familial Mediterranean Fever allele
- C;CBadFamilial Mediterranean Fever risk
SNPedia records rs28940577 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other MEFV SNPs
- i4000404T;TFamilial Mediterranean FeverVery important
- i4000406C;Cfamilial mediterranean feverVery important
- i4000410T;Tfamilial mediterranean feverVery important
- rs28940580C;GFamilial mediterranean fever (predicted)Very important
- rs61732874A;Afamilial mediterranean feverVery important
- rs61752717C;Cfamilial mediterranean feverVery important
- rs104895093-;-Familial Mediterranean FeverVery important
- rs104895094C;CFamilial Mediterranean Fever, autosomal recessiveVery important
Notes
From SNPedia
Notes
C;T
Possibly: predisposition for fibromyalgia syndrome
C;C
Possibly: predisposition for fibromyalgia syndrome
Source and license
Adapted from rs28940577 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.