rs37022
A SNP in the SLC6A3 gene on chromosome 5. Its most notable genotype is A;A: common in complete genomics
- Gene
- SLC6A3
- Location
- Chr 51,415,514 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 34%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs37022 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageA;A 34%
- European ancestry (Utah)A;A 60%
- Han Chinese (Beijing)A;A 24%
- Japanese (Tokyo)A;A 23%
- Yoruba (Nigeria)A;A 29%
Related
Other SLC6A3 SNPs
- rs267607068T;TInfantile Parkinsonism-dystoniaVery important
- rs267607069A;AInfantile Parkinsonism-dystoniaVery important
- rs431905504T;TInfantile Parkinsonism-dystoniaVery important
- rs431905514T;TInfantile Parkinsonism-dystoniaVery important
- rs431905515G;GInfantile Parkinsonism-dystoniaVery important
- rs431905516A;AInfantile Parkinsonism-dystoniaVery important
- rs27072C;C2x risk of severe alcohol withdrawal. Possible increased odds of ADHD.Worth knowing
- rs460000G;GBetter response to amphetamineWorth knowing
Notes
From SNPedia
Notes
D2 dopamine receptor gene haplotypes and their influence on alcohol and tobacco consumption magnitude in alcohol-dependent individuals. Neurotransmission and bipolar disorder: a systematic family-based association study. Association of tagging single nucleotide polymorphisms on 8 candidate genes in dopaminergic pathway with schizophrenia in Croatian population. Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.
Source and license
Adapted from rs37022 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.