rs431905514
A SNP in the SLC6A3 gene on chromosome 5. Its most notable genotype is T;T: Infantile Parkinsonism-dystonia
- Gene
- SLC6A3
- Location
- Chr 51,416,097 (GRCh38)
- Highest magnitude
- 8.0Very important
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- T;TMost notableBadInfantile Parkinsonism-dystonia
- C;TBadCarrier of an infantile Parkinsonism-dystonia mutation
- C;CGoodcommon in clinvar
SNPedia records rs431905514 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other SLC6A3 SNPs
- rs267607068T;TInfantile Parkinsonism-dystoniaVery important
- rs267607069A;AInfantile Parkinsonism-dystoniaVery important
- rs431905504T;TInfantile Parkinsonism-dystoniaVery important
- rs431905515G;GInfantile Parkinsonism-dystoniaVery important
- rs431905516A;AInfantile Parkinsonism-dystoniaVery important
- rs27072C;C2x risk of severe alcohol withdrawal. Possible increased odds of ADHD.Worth knowing
- rs460000G;GBetter response to amphetamineWorth knowing
- rs464049G;Gdecreased risk of schizophrenia in limited studyMinor
Notes
From SNPedia
Notes
c.1031+1G>A
T;T
See SLC6A3
C;T
Unaffected in absence of a second SLC6A3 mutation; see SLC6A3
Source and license
Adapted from rs431905514 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.