rs3842
A SNP in the ABCB1 gene on chromosome 7. Its most notable genotype is T;T.
- Gene
- ABCB1
- Location
- Chr 787,504,050 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 20%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs3842 on the minus strand: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 10 HapMap populations.
- AverageT;T 64%
- European ancestry (Utah)T;T 75%
- Han Chinese (Beijing)T;T 52%
- Yoruba (Nigeria)T;T 75%
- African ancestry (Southwest US)T;T 68%
- Chinese (Denver)T;T 52%
- Gujarati IndianT;T 67%
- Luhya (Kenya)T;T 60%
- Mexican ancestry (Los Angeles)T;T 60%
- Maasai (Kenya)T;T 55%
- TuscanT;T 77%
Related
Conditions, medicines and genes
Other ABCB1 SNPs
- rs1045642A;Aaltered drug metabolism and bioavailability; moderately increased risk for certain cancersImportant
- rs2032582T;Trare genotype, on a triallelic snpMinor
- rs2235040T;Tpossibly higher chances of remission only for inpatients on certain antidepressantsMinor
- rs10248420A;Apossibly less likely to remit on certain antidepressantsMinor
- rs4148739C;Tpossibly, inpatients more likely to remit on certain antidepressantsMinor
- rs1128503G;GnormalTypical
- rs2032583G;GNo summary available.Typical
- rs2214102C;Ccommon in complete genomicsTypical
Notes
From SNPedia
Notes
rs3842 (A;G) and (G;G) was associated with increased risk of developing lung cancer (odds ratio [OR]. 1.36; 95% confidence interval [95% CI], 1.06-1.76), especially in women (2.5x) rs212090(A;T) (T;T) increased cancer susceptibility (OR, 1.37; 95% CI, 1.03-1.83)
Source and license
Adapted from rs3842 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.